With only a few episodes left in From Season 4, the MGM+ horror series has taken another bold leap into science fiction. This week's installment, "Best Laid Plans," delivers a twist that will feel eerily familiar to fans of Lost—a full-blown alternate reality. The episode sees Henry (Robert Joy) poisoned by Sophia (Julia Doyle), aka the Man in the Yellow Suit (Douglas E. Hughes), who spikes his drink with her blood. What follows is a hallucinatory journey where Henry wakes from a 40-year coma to find his son Victor (Scott McCord) by his side.

Collider spoke with McCord and Joy about this surprising development, the effects of Sophia's poisoning, and the deepening bond between Victor and Ethan (Simon Webster). The actors also touched on how the twist forced them to "invent a new history" for their characters, adding layers to an already complex narrative.

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The Poisoning That Changed Everything

Joy admitted he didn't see the poisoning coming until he read the script. "It was exciting to play because I didn't know until I got that script for that episode that Sophia and Henry would have that connection," he said. "When she shows up with the minister, and then you realize that she's a maligned force—she's actually a very maligned force—I didn't know how they were going to have her navigate."

The actor described the experience as "almost like an acid trip," noting that Sophia's blood "opens the doors of perception" and fundamentally alters Henry's brain. "I'm still not sure how that's going to play out, even though I know what happened at the end of this scene. Where do you go from there?" Joy added, hinting at lingering consequences.

Victor and Ethan: A Bond Beyond Trauma

McCord, who plays the enigmatic Victor, highlighted the character's protective relationship with Ethan. "I think [Victor] sees so much of himself in [Ethan]," he explained. "With the further developments of this relationship and story as it goes from here forward, there's also a protective nature there. There's a brother relationship there, brother-brother, but there's a symbiosis."

The actor pointed to their first meeting in Season 1, when Ethan mentioned seeing the boy in white, as the spark that ignited their connection. "They're really connected as brothers, I suppose," McCord said. "I think Victor was carrying and has been carrying a lot of guilt about the loss of Jim, as well, with the idea that knowledge comes at a cost. This is at the crux of Victor's torment. 'How can I help? How can I do this?'"

Joy added that Victor's experience with trauma makes him uniquely suited to protect Ethan. "There's not much new to Victor," he said. "And in a way, I feel like one of the ways he protects Ethan is with his experience. You've gone through trauma, and you're trying to save him to spare him."

Inventing a New History

Both actors emphasized the challenge of playing characters whose pasts are being rewritten. "We had to invent a new history for our characters," McCord revealed. "The alternate reality forces us to reconsider everything we thought we knew about Victor and Henry." Joy agreed, noting that the twist opens up new emotional territory. "It's like we're meeting them for the first time again," he said.

For fans of the series, this episode marks a turning point. As From continues to blur the lines between horror and sci-fi, the alternate reality twist promises to reshape the show's mythology. With only a few episodes left, viewers can expect more surprises—and more heartbreak—as the story hurtles toward its season finale.